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 Remdesivir is a nucleoside analogue, an RNA-dependent RNA polymerase (RdRp) inhibitor that can synthesize antivirals by inhibiting viral nucleic acids. Clinical studies of Ebola virus infection are currently in phase II. Mice infected with MERS performed much better after receiving this combination therapy, with reduced viral replication and improved lung function.

Redsivir is a precursory drug for nucleotide analogues. In vitro experimental and animal model data show that Redsiwe inhibits a variety of coronaviruses, including atypical pneumonia (SARS coronavirus), Middle East Respiratory Syndrome (MERS coronavirus), Ebola coronavirus, and many other coronaviruses, by inhibiting RNA-derived RNApolymerase(RdRp). In vitro cell experiments showed that half of Redsivir's effective concentration of the new coronavirus (IC50) was 0.77 mol. L-1。

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